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Blocking of BBOX1 in PDAC and CAF cell lines in vitro (A) Concentration of carnitine and acetylcarnitine in KPC flox -derived PDAC cell lines (146, 147, and 244) after treatment with meldonium for 24 h. Data are means ± SE. ∗, p < 0.05; ∗∗, p < 0.01 by non-parametric Shirley-Williams’ test. (B) Cell viabilities of PDAC cell lines (146, 147, and 244) and human pancreatic stellate cell (hPSC-1, 5, and 14) lines after treatment with meldonium for 24 h. Data are means ± SE. (C) Relative intensities of <t>cytokine</t> levels in the cytokine antibody array using pooled supernatant of mouse PDAC cell lines (146, 147, and 244) treated with vehicle (V) or meldonium (M) for 48 h. Data are presented as the means of two array spots. Also see and .
C Series Mouse Cytokine Antibody Array, supplied by RayBiotech inc, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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c series mouse cytokine antibody array - by Bioz Stars, 2026-10
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Blocking of BBOX1 in PDAC and CAF cell lines in vitro (A) Concentration of carnitine and acetylcarnitine in KPC flox -derived PDAC cell lines (146, 147, and 244) after treatment with meldonium for 24 h. Data are means ± SE. ∗, p < 0.05; ∗∗, p < 0.01 by non-parametric Shirley-Williams’ test. (B) Cell viabilities of PDAC cell lines (146, 147, and 244) and human pancreatic stellate cell (hPSC-1, 5, and 14) lines after treatment with meldonium for 24 h. Data are means ± SE. (C) Relative intensities of <t>cytokine</t> levels in the cytokine antibody array using pooled supernatant of mouse PDAC cell lines (146, 147, and 244) treated with vehicle (V) or meldonium (M) for 48 h. Data are presented as the means of two array spots. Also see and .
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Blocking of BBOX1 in PDAC and CAF cell lines in vitro (A) Concentration of carnitine and acetylcarnitine in KPC flox -derived PDAC cell lines (146, 147, and 244) after treatment with meldonium for 24 h. Data are means ± SE. ∗, p < 0.05; ∗∗, p < 0.01 by non-parametric Shirley-Williams’ test. (B) Cell viabilities of PDAC cell lines (146, 147, and 244) and human pancreatic stellate cell (hPSC-1, 5, and 14) lines after treatment with meldonium for 24 h. Data are means ± SE. (C) Relative intensities of <t>cytokine</t> levels in the cytokine antibody array using pooled supernatant of mouse PDAC cell lines (146, 147, and 244) treated with vehicle (V) or meldonium (M) for 48 h. Data are presented as the means of two array spots. Also see and .
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Blocking of BBOX1 in PDAC and CAF cell lines in vitro (A) Concentration of carnitine and acetylcarnitine in KPC flox -derived PDAC cell lines (146, 147, and 244) after treatment with meldonium for 24 h. Data are means ± SE. ∗, p < 0.05; ∗∗, p < 0.01 by non-parametric Shirley-Williams’ test. (B) Cell viabilities of PDAC cell lines (146, 147, and 244) and human pancreatic stellate cell (hPSC-1, 5, and 14) lines after treatment with meldonium for 24 h. Data are means ± SE. (C) Relative intensities of <t>cytokine</t> levels in the cytokine antibody array using pooled supernatant of mouse PDAC cell lines (146, 147, and 244) treated with vehicle (V) or meldonium (M) for 48 h. Data are presented as the means of two array spots. Also see and .
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Blocking of BBOX1 in PDAC and CAF cell lines in vitro (A) Concentration of carnitine and acetylcarnitine in KPC flox -derived PDAC cell lines (146, 147, and 244) after treatment with meldonium for 24 h. Data are means ± SE. ∗, p < 0.05; ∗∗, p < 0.01 by non-parametric Shirley-Williams’ test. (B) Cell viabilities of PDAC cell lines (146, 147, and 244) and human pancreatic stellate cell (hPSC-1, 5, and 14) lines after treatment with meldonium for 24 h. Data are means ± SE. (C) Relative intensities of <t>cytokine</t> levels in the cytokine antibody array using pooled supernatant of mouse PDAC cell lines (146, 147, and 244) treated with vehicle (V) or meldonium (M) for 48 h. Data are presented as the means of two array spots. Also see and .
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Blocking of BBOX1 in PDAC and CAF cell lines in vitro (A) Concentration of carnitine and acetylcarnitine in KPC flox -derived PDAC cell lines (146, 147, and 244) after treatment with meldonium for 24 h. Data are means ± SE. ∗, p < 0.05; ∗∗, p < 0.01 by non-parametric Shirley-Williams’ test. (B) Cell viabilities of PDAC cell lines (146, 147, and 244) and human pancreatic stellate cell (hPSC-1, 5, and 14) lines after treatment with meldonium for 24 h. Data are means ± SE. (C) Relative intensities of <t>cytokine</t> levels in the cytokine antibody array using pooled supernatant of mouse PDAC cell lines (146, 147, and 244) treated with vehicle (V) or meldonium (M) for 48 h. Data are presented as the means of two array spots. Also see and .
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Blocking of BBOX1 in PDAC and CAF cell lines in vitro (A) Concentration of carnitine and acetylcarnitine in KPC flox -derived PDAC cell lines (146, 147, and 244) after treatment with meldonium for 24 h. Data are means ± SE. ∗, p < 0.05; ∗∗, p < 0.01 by non-parametric Shirley-Williams’ test. (B) Cell viabilities of PDAC cell lines (146, 147, and 244) and human pancreatic stellate cell (hPSC-1, 5, and 14) lines after treatment with meldonium for 24 h. Data are means ± SE. (C) Relative intensities of <t>cytokine</t> levels in the cytokine antibody array using pooled supernatant of mouse PDAC cell lines (146, 147, and 244) treated with vehicle (V) or meldonium (M) for 48 h. Data are presented as the means of two array spots. Also see and .
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Blocking of BBOX1 in PDAC and CAF cell lines in vitro (A) Concentration of carnitine and acetylcarnitine in KPC flox -derived PDAC cell lines (146, 147, and 244) after treatment with meldonium for 24 h. Data are means ± SE. ∗, p < 0.05; ∗∗, p < 0.01 by non-parametric Shirley-Williams’ test. (B) Cell viabilities of PDAC cell lines (146, 147, and 244) and human pancreatic stellate cell (hPSC-1, 5, and 14) lines after treatment with meldonium for 24 h. Data are means ± SE. (C) Relative intensities of <t>cytokine</t> levels in the cytokine antibody array using pooled supernatant of mouse PDAC cell lines (146, 147, and 244) treated with vehicle (V) or meldonium (M) for 48 h. Data are presented as the means of two array spots. Also see and .
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Blocking of BBOX1 in PDAC and CAF cell lines in vitro (A) Concentration of carnitine and acetylcarnitine in KPC flox -derived PDAC cell lines (146, 147, and 244) after treatment with meldonium for 24 h. Data are means ± SE. ∗, p < 0.05; ∗∗, p < 0.01 by non-parametric Shirley-Williams’ test. (B) Cell viabilities of PDAC cell lines (146, 147, and 244) and human pancreatic stellate cell (hPSC-1, 5, and 14) lines after treatment with meldonium for 24 h. Data are means ± SE. (C) Relative intensities of cytokine levels in the cytokine antibody array using pooled supernatant of mouse PDAC cell lines (146, 147, and 244) treated with vehicle (V) or meldonium (M) for 48 h. Data are presented as the means of two array spots. Also see and .

Journal: iScience

Article Title: Blocking L-carnitine synthesis by meldonium prolongs the survival in mice with pancreatic cancer

doi: 10.1016/j.isci.2026.117071

Figure Lengend Snippet: Blocking of BBOX1 in PDAC and CAF cell lines in vitro (A) Concentration of carnitine and acetylcarnitine in KPC flox -derived PDAC cell lines (146, 147, and 244) after treatment with meldonium for 24 h. Data are means ± SE. ∗, p < 0.05; ∗∗, p < 0.01 by non-parametric Shirley-Williams’ test. (B) Cell viabilities of PDAC cell lines (146, 147, and 244) and human pancreatic stellate cell (hPSC-1, 5, and 14) lines after treatment with meldonium for 24 h. Data are means ± SE. (C) Relative intensities of cytokine levels in the cytokine antibody array using pooled supernatant of mouse PDAC cell lines (146, 147, and 244) treated with vehicle (V) or meldonium (M) for 48 h. Data are presented as the means of two array spots. Also see and .

Article Snippet: RayBio C-series mouse cytokine antibody array , RayBiotech , Cat# AAM-CYT-3.

Techniques: Blocking Assay, In Vitro, Concentration Assay, Derivative Assay, Ab Array